{"id":2147,"date":"2021-09-19T10:44:59","date_gmt":"2021-09-19T10:44:59","guid":{"rendered":"http:\/\/khoo.com.au\/?page_id=2147"},"modified":"2021-09-19T10:44:59","modified_gmt":"2021-09-19T10:44:59","slug":"the-pfizer-comirnaty-vaccine","status":"publish","type":"page","link":"https:\/\/khoo.com.au\/index.php\/the-pfizer-comirnaty-vaccine\/","title":{"rendered":"The Pfizer Comirnaty vaccine"},"content":{"rendered":"\n<p>17th September 2021, Dr Chee L Khoo<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"318\" src=\"http:\/\/khoo.com.au\/wp-content\/uploads\/2021\/01\/virus_vaccine_injection_800_clr_23352.png\" alt=\"\" class=\"wp-image-2093\" srcset=\"https:\/\/khoo.com.au\/wp-content\/uploads\/2021\/01\/virus_vaccine_injection_800_clr_23352.png 800w, https:\/\/khoo.com.au\/wp-content\/uploads\/2021\/01\/virus_vaccine_injection_800_clr_23352-300x119.png 300w, https:\/\/khoo.com.au\/wp-content\/uploads\/2021\/01\/virus_vaccine_injection_800_clr_23352-768x305.png 768w, https:\/\/khoo.com.au\/wp-content\/uploads\/2021\/01\/virus_vaccine_injection_800_clr_23352-465x185.png 465w, https:\/\/khoo.com.au\/wp-content\/uploads\/2021\/01\/virus_vaccine_injection_800_clr_23352-695x276.png 695w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p>The <strong>Pfizer Comirnaty COVID-19 vaccine<\/strong> is an <strong>mRNA<\/strong>\nvaccine which is designed to induce an antibody response against the <strong>spike\nprotein<\/strong> of the covid-19 virus. It contains the genetic code for the spike\nprotein. It <strong>does not<\/strong> contain any live virus, and it cannot give you\nCOVID-19. After getting the vaccine, your body makes copies of the spike\nprotein. Your immune system respond by raising antibodies against the spike\nprotein. If and when covid-19 virus ever attack you, the pre-formed antibodies\nare ready and will help reduce your chances of catching the infection. It also\nsignificantly reduce the severity of disease if you catch covid-19 infection\ndespite the vaccination. Your chance of dying or being on a ventilator if you\ncatch covid-19 is reduced by 90-95%. It also reduces transmission of the virus\nto someone else.<\/p>\n\n\n\n<p><strong>Comirnaty <\/strong>is effective in preventing COVID-19 in people aged\n12 years and older. People who had two doses of <strong>Comirnaty<\/strong>were about 95 % less likely to get symptomatic COVID-19 than people who did\nnot get the vaccine. It was equally effective in people over the age of 65\nyears, as well as people with some stable pre-existing medical conditions.<\/p>\n\n\n\n<p>Protection against COVID-19 starts from about 2\u20133 weeks after the first\ndose. While one dose may give some protection, it may only last for the\nshort-term. Two doses, generally given 3-4 weeks apart, will give optimal\nprotection. No vaccine is 100 % effective, so it is possible that you can still\nget sick from COVID-19 after vaccination. We do not know for sure how long the\nprotection from <strong>Comirnaty<\/strong>will last but\nrecent studies suggest that at 6 months, the vaccine is still protective. More studies\nare pending. It is likely that we will need booster shots in the near future\nbut we don\u2019t know when and which vaccine yet.<\/p>\n\n\n\n<p>Pregnant women with COVID-19 have an increased risk of severe illness and\nadverse pregnancy outcomes. Real-world evidence has shown that <strong>Comirnaty<\/strong>is safe for pregnant women and breastfeeding women. If you are\nbreastfeeding, you can have <strong>Comirnaty<\/strong>. You do not need to stop\nbreastfeeding after vaccination.<\/p>\n\n\n\n<p><strong>Who may not be suitable to have the Pfizer vaccine<\/strong><\/p>\n\n\n\n<p>As a precaution, people with a history of any of the following conditions\ncan receive <strong>Comirnaty<\/strong>but advice should\nbe sought from a GP, immunisation specialist or cardiologist about the best\ntiming of vaccination and whether any additional precautions are recommended:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Recent (i.e. within the past 6 months) or current inflammatory cardiac\nillness e.g., myocarditis, pericarditis, endocarditis <\/li><li>Acute rheumatic fever (i.e., with active myocardial inflammation) or acute\nrheumatic heart disease<\/li><li>Dilated cardiomyopathy (for people under 30 years of age)<\/li><li>Congenital heart disease<\/li><li>Severe heart failure<\/li><li>Heart transplant recipients<\/li><\/ul>\n\n\n\n<p><strong>People with reduced immune systems<\/strong><\/p>\n\n\n\n<p>The Australian Government strongly recommends people with\nimmune-compromise receive COVID-19 vaccination. <strong>Comirnaty <\/strong>is not a live\nvaccine. It is safe in people with immunocompromise. There is no particular\nharm to have the vaccine because the vaccine do not contain any live viruses\nbut the <strong>effectiveness<\/strong> of the vaccine may not be as good. Some\nimmunosuppressive drugs may need to be adjusted prior to the vaccination. You\nshould discuss with your specialist or GP prior to the vaccination.<\/p>\n\n\n\n<p><strong>Myocarditis after Comirnaty vaccine<\/strong><\/p>\n\n\n\n<p>There have been reports of myocarditis following Comirnaty\nand (Moderna) Spikevax vaccination. After 177 million doses of Comirnaty and 20\nmillion Spikevax administered, the incidence of myocarditis is reported to be\nabout 1 in a million doses administered. Most of those affected were young men.\n<\/p>\n\n\n\n<p>Myocarditis is inflammation of the heart muscle. Patients\nwith myocarditis may complain of chest pains, palpitations, shortness of breath,\nfatigue, nausea, vomiting or abdominal pain between 2-7 days after the second\ndose. Only a few patients require hospitalisation and all patients fully\nrecover with no long term damage. <\/p>\n\n\n\n<p>Obviously, the risk of cardiac complications due to\nSARS-CoV-2 infection far exceeds the minimal and rare risks of vaccination-related\ntransient myocardial or pericardial inflammation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>17th September 2021, Dr Chee L Khoo The Pfizer Comirnaty COVID-19 vaccine is an mRNA vaccine which is designed to induce an antibody response against the spike protein of the covid-19 virus. It contains the genetic code for the spike protein. It does not contain any live virus, and it<span class=\"more-link\"><a href=\"https:\/\/khoo.com.au\/index.php\/the-pfizer-comirnaty-vaccine\/\">Continue Reading<\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["entry","author-chee1404","post-2147","page","type-page","status-publish"],"_links":{"self":[{"href":"https:\/\/khoo.com.au\/index.php\/wp-json\/wp\/v2\/pages\/2147","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/khoo.com.au\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/khoo.com.au\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/khoo.com.au\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/khoo.com.au\/index.php\/wp-json\/wp\/v2\/comments?post=2147"}],"version-history":[{"count":1,"href":"https:\/\/khoo.com.au\/index.php\/wp-json\/wp\/v2\/pages\/2147\/revisions"}],"predecessor-version":[{"id":2148,"href":"https:\/\/khoo.com.au\/index.php\/wp-json\/wp\/v2\/pages\/2147\/revisions\/2148"}],"wp:attachment":[{"href":"https:\/\/khoo.com.au\/index.php\/wp-json\/wp\/v2\/media?parent=2147"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}